TOYOBO

Cosmetics Ingredients in Japanese

CERAMELA

CERAMELA is

Ceramide-like biohumectant produced by a plant yeast and olive oil.

CERAMELA consists of fatty acid from olive oil, mannose and erythritol. Two lipid chains are bound to sugar, so that the structure and functions resemble ceramide.

CERAMELA consists of fatty acids from olive oil, mannose and erythritol. Two lipid chains are bound to sugar, so that the structure and functions resemble ceramide.

Skin barrier function

The stratum corneum has a regular crystalline structure called the "lamella." The lamella is essential to keeping moisture in the stratum corneum so that it may act as a barrier. When ceramide, the oil component of lamella, is lacking, the moisture content reduces, causing the skin to be rough.
Ceramela replenishes the lamella in the stratum corneum and compensates for the reduced moisture retention due to the lack of ceramide, thus improving rough skin. Ceramela is expected to be a useful skin-care material that is highly safe for use on hypersensitive skin that responds adversely to external stimuli.

Skin barrier functions

Features of CERAMELA

Excellent penetrationOnly 30 minutes after applying the Ceramela solution to the skin,
it penetrates the stratum corneum.

Only 30 minutes after applying the Ceramela solution to the skin, it penetrates the stratum corneum.
[Testing method]
  • Skin tested: Resected human skin (Produced by ILAM Company in USA)
  • Diffusion cell: Franz type diffusion cell
  • Test sample: 1% NBD-Ceramela solution containing 35% 1,3-BG
  • Photography: Fluorescence microscope
CERAMELA has high-affinity to human skin

CERAMELA has high affinity to human skin

Lasting moisturizing effect after application

Ceramela exerts its moisturizing effect by reinforcing the skin's barrier function.
Even after application is discontinued, skin retains a high moisture content.

Ceramela exerts its moisturizing effect by reinforcing the skin's barrier function. Even after application is discontinued, skin retains a high moisture content.
  • non: Not applied
  • BG: 3% 1,3-butylene glycol (BG)
  • GC: 0.2% glucosylceramide (3% BG)
  • Ceramela: 0.2% Ceramela (3% BG)

Texture improving effectDestroyed texture due to rough skin is repaired shortly after the application of Ceramela.

Destroyed texture due to rough skin is repaired shortly after the application of Ceramela.
[Methods]

Apply a transparent double-sided tape (Scotch Company) onto the medial side of the forearm, and peel it off.
Repeat this procedure 5 times to cause rough skin. Apply Ceramela (0.2%, 3% BG) onto the test area, and observe the skin surface with a microscope 60 minutes after application.

Product information

  • CERAMELA-PX (Premix)
  • CERAMELA-HBG (CERAMELA-HG 50% / BG 50%)
  • CERAMELA-HG (Pure type)

CERAMELA-PX (Premix)

Product name CERAMELA-PX
Product code MEL-209
INCI name(Concentration) Water/Glycolipids(10%)/Glycerin/Propanediol/Dipotassium Glycyrrhizate/Citric acid
CAS RN 7732-18-5/1264282-45-2/56-81-5/504-63-2/68797-35-3/5949-29-1
Appearance Light yellow, ď˝”ransparent ~semi-transparent viscous liquid
Major characteristics All natural origin ingredients
Easy formulation for aqueous solution
Free from artificial preservative and colorants
Shelf life 1 year under unopened cool and dark storage
Package size 1kg
Recommendable dosage 1~10%

CERAMELA-HBG (CERAMELA-HG 50% / BG 50%)

Product name CERAMELA-HBG
Product code MEL-211
INCI name Glycolipids Butylene Glycol
CAS RN 1264282-45-2 107-88-0
Composition Approx.50% Approx.50%
Appearance Yellow ~ Orange liquid
Solubility Well soluble in polyalcohol except for glycerol.
Soluble in water with surfactant.
Shelf life 1 year under unopened cool and dark storage
Package size 1kg
Miscellaneous All natural origin ingredients with plant-derived 1,3-Butylene Glycol
Recommendable dosage 0.2~2.0%

CERAMELA-HG (Pure type)

Product name CERAMELA-HG
Product code MEL-201
INCI name Glycolipids
CAS RN 1264282-45-2
Purity (HPLC) ≥95%
Appearance Yellow ~ Orange oily liquid
Solubility Well soluble in polyalcohol except for glycerol.
Soluble in water with surfactant.
Shelf life 1 year under unopened cool and dark storage
Package size 1kg
Miscellaneous Free from artificial preservatives, buffer, colorants and antioxidants
Recommendable dosage 0.1~1.0%

In use

  • Refer to SDS (Safety Data Sheet) we provide upon request.
  • The product contains no preservatives. Please use immediately after opening the container.
  • In using CERAMELA, please assure conformance to product safety or any other legal regulations, and avoidance of infringement to intellectual properties of third parties.

Back to top

Copyright(C) 1996-2013 TOYOBO CO., LTD. All rights reserved.