CATAROSEV™

CATAROSEV™ is a product that uses a precision microfiltration membrane developed by Toyobo, which possesses both ion‑exchange functionality and size‑based separation capability. By leveraging the size and charge characteristics of small EVs, it enables their efficient, high‑purity separation and recovery in a short amount of time.

Mechanism of CATAROSEV™

CATAROSEV™ separates small EVs based on charge (ion-exchange functionality) and size (approximately 200-nm pore size).

Workflow

1. Adsorption Step : small EVs are adsorbed onto the membrane, using the charges on the ssmall EVs surface.
2. Wash Step : Uncharged impurities are removed.
3. Elution Step : small EVs that are adsorbed to the membrane are collected using a high-salt buffer.